Which Weight Loss Medications Actually Work?

According to the CDC, nearly 3 out of 4 adults in the U.S. are overweight or obese. This shows that effective weight loss is a complex challenge, not a matter of willpower. And among the many medications available, GLP-1s like semaglutide and tirzepatide consistently deliver the most significant results.

At Doctors Weight Loss in Laguna Hills, California, we take a personalized approach that goes beyond prescriptions. Our team evaluates your health, lifestyle, and goals to recommend a personalized, safe, and effective treatment plan that may include weight loss medication, nutritional guidance, and ongoing support. 

Weight loss medication isn’t a one-size-fits-all solution. Results depend on consistency, your overall health, and the support you receive. That said, medications like semaglutide and tirzepatide particularly go far beyond what exercise and diet often achieve, and the research shows just how powerful they can be.

Understanding the power of semaglutide and tirzepatide

Even though the weight loss industry is full of “miracle” products that overpromise and underdeliver, today’s prescription weight loss medications have scientific backing.

Clinical studies show that medications like semaglutide and tirzepatide can support substantial weight loss when paired with healthy habits. 

A New England Journal of Medicine study found that participants who took semaglutide (Wegovy) in conjunction with healthy lifestyle changes lost about 15% of their body weight over 68 weeks. Another study found tirzepatide (Zepbound) helped participants lose up to 20% over roughly a year and a half. 

These are among the most significant results ever achieved with weight loss medication. 

Even modest drops in weight make a big difference. Research from the American Heart Association shows that losing just 5-10% of extra pounds can lower blood pressure, improve blood sugar, and reduce your risk of heart disease. 

However, results vary based on dose, duration, and adherence. Outside of clinical trials, people may not lose as much weight because they may stop treatment early or not take the full dose as prescribed. Medical guidance can help you stay consistent, make any needed adjustments, and achieve your desired results. 

If you’re considering weight loss medication, our team explains the process and set realistic expectations. 

Take your next step to a healthier you 

Doctors Weight Loss in Laguna Hills, California, can help you determine which weight loss medication, if any, is right for your body and goals. We offer individual medical weight loss plans tailored to your needs and want to help you feel your best. Schedule your appointment for a consultation.