What Men Should Know About Testosterone Replacement Therapy

Sep 26, 2025
What Men Should Know About Testosterone Replacement Therapy
Low testosterone can affect energy, mood, muscle, and libido. But testosterone replacement therapy (TRT) may help restore balance. Here's what you need to know.

Low libido. Less muscle. Many men chalk up these changes to aging, but sometimes the real culprit is low testosterone. 

Also called low-T, or hypogonadism, this condition develops when your testicles don’t produce enough of the hormone. This is common as men age, and testosterone replacement therapy, or TRT, can restore hormone levels to a healthy range. 

At Doctors Weight Loss in Laguna Hills, California, we address the emotional, physical, and cognitive changes that happen as men age and recommend the next best step. For some men,  TRT transforms energy, mood, and performance. But it isn’t for everyone. 

Before you jump in, it helps to know the facts, benefits, and possible downsides.  Here’s what to keep in mind if you’re considering this popular treatment. 

What is testosterone? 

Often called the “male” hormone, testosterone is primarily made in the testicles and helps maintain your:

  • Bone density 
  • Muscle mass 
  • Sex drive 
  • Sperm production 
  • Fat distribution 

When testosterone levels are healthy, these functions run smoothly. But when levels drop too low, you may notice symptoms. 

Why do men consider TRT? 

Remember your twenties? You probably had plenty of energy and a sex drive that didn’t need much encouragement. That’s because testosterone peaks in your teens and early adulthood and starts naturally declining as you age. 

Most men lose about 1% of testosterone each year after turning 30. For some men, the drop leads to symptoms that impact their daily lives. 

You might notice: 

  • Low energy 
  • Less motivation 
  • Reduced muscle mass 
  • Mood changes 
  • Decreased sex drive 
  • Trouble concentrating
  • Hair loss (in some cases) 

While these symptoms can have many causes, low T is one possibility. Bloodwork is the only way to confirm. 

How does TRT work? 

TRT replenishes testosterone, restoring your levels to a healthy range. Delivery methods include: 

  • Topical gels or creams 
  • Injections (at home or in the clinic) 
  • Pellets inserted under your skin 
  • Patches worn on the skin 

Our healthcare providers help you choose the option that best fits your needs. 

What are the potential benefits of TRT? 

When testosterone returns to normal, many men report: 

  • Better energy and stamina
  • Improved mood and focus 
  • Increased muscle mass and strength
  • Stronger sexual function and libido 
  • More confidence 

However, TRT isn’t right for everyone, as there are risks. 

What are the risks of TRT?

TRT doesn’t come without drawbacks. In some cases, testosterone therapy can cause the following:

Blood clots

Too many red blood cells can thicken your blood, making it easier for clots to form. Blood clots can block blood flow, leading to a heart attack or stroke.

Increased sleep apnea symptoms

If you already have sleep apnea, a condition that causes your breathing to stop and start while sleeping, TRT may exacerbate it. 

Fertility issues 

TRT can lower sperm count, which could affect fertility if you’re planning to have children. 

Starting TRT treatments means committing to regular follow-up care, including blood work and health check-ins.

Support your health with expert care   

TRT can be life-changing for men with clinically low testosterone, but it’s not a cure-all. Partner with experienced healthcare professionals to determine whether it makes sense for you. 

If you’re experiencing these symptoms, our team at Doctors Weight Loss in Laguna Hills, California, can help. We evaluate your symptoms and guide you to the next step. Call us or request an appointment online today.